Description

H-Gly-Gly-Glu-Ala-Oh is a synthetic tetrapeptide composed of the amino acids glycine, glutamic acid, and alanine. This compound is valued for its role as a key intermediate in peptide synthesis and biochemical research, offering precise structural control. It is primarily utilized by pharmaceutical R&D departments, biotechnology companies, and academic research institutions focused on developing novel therapeutic peptides and studying enzyme substrates.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of longer, more complex therapeutic peptides and peptidomimetics.
• Biochemical Research: Used as a standard or substrate in enzymatic studies, particularly for proteases and peptidases.
• Cosmetic Peptide Synthesis: Serves as a precursor for bioactive peptides used in advanced skincare formulations targeting specific skin functions.
• Academic & Industrial R&D: Employed in structure-activity relationship (SAR) studies to understand peptide function and design new bioactive molecules.
• Diagnostic Reagent Development: Potential use in the development of assay components and calibration standards for diagnostic kits.

Basic Information

Product Name	H-Gly-Gly-Glu-Ala-Oh
CAS No.	68171-98-2
Molecular Formula	C13H21N5O8
Molecular Weight	375.34 g/mol
Synonyms	Glycyl-glycyl-L-glutamyl-L-alanine; GGE; Gly-Gly-Glu-Ala; L-Alanine, L-α-glutamylglycylglycyl-; Tetrapeptide G-G-E-A; H-Gly-Gly-Glu-Ala-OH; G-G-E-A-OH; (2S)-2-[[(2S)-2-[[2-[(2-aminoacetyl)amino]acetyl]amino]-4-carboxybutanoyl]amino]propanoic acid
EINECS	Contact for details

Quality Control

Our H-Gly-Gly-Glu-Ala-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, residual solvents, and heavy metals is provided with every shipment to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0% (on anhydrous basis)
Optical Rotation	Specific range available on COA
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.