Description

Gacyclidine is a high-purity, non-competitive NMDA receptor antagonist with significant research and pharmaceutical interest. This compound is valued for its potent and selective action on the central nervous system, making it a critical reference standard and intermediate in advanced studies. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and specialty chemical manufacturers focused on neuropharmacology and CNS drug discovery.

Application

• Neuropharmacological Research: As a potent NMDA receptor antagonist for studying excitotoxicity, neuroprotection, and synaptic plasticity.
• Reference Standard: For analytical method development, validation, and quality control in pharmaceutical laboratories.
• Pharmaceutical Intermediate: In the synthesis and development of novel therapeutics targeting neurological and psychiatric disorders.
• Mechanistic Studies: For investigating the role of NMDA receptors in conditions such as stroke, traumatic brain injury, and chronic pain.
• Preclinical Development: Serves as a key compound in the early-stage drug discovery pipeline for CNS-targeted agents.

Basic Information

Product Name	Gacyclidine
CAS No.	68134-81-6
Molecular Formula	C17H25N
Molecular Weight	243.39 g/mol
Synonyms	GK-11; Phencyclidine derivative GK-11; TCP; 1-[1-(2-Thienyl)cyclohexyl]piperidine; Thienylcyclohexylpiperidine; GK11; GK 11
EINECS	Contact for details

Quality Control

Our Gacyclidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry guidelines for research-grade chemicals, ensuring reliable performance for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.