Description

Norfloxacinehydrochloride CAS NO 68077-27-0 is the hydrochloride salt form of the broad-spectrum fluoroquinolone antibiotic, norfloxacin. This form enhances the compound's stability and solubility, making it a critical active pharmaceutical ingredient (API) for the formulation of various medicinal products. It is essential for manufacturers in the pharmaceutical industry requiring a reliable, high-purity intermediate for producing effective antibacterial treatments.

Application

• Pharmaceutical API: Primary use as an active pharmaceutical ingredient in the manufacture of antibacterial medications.
• Veterinary Medicine: Formulation of antibacterial treatments for veterinary applications.
• Research & Development: Serves as a key reference standard and intermediate in pharmacological and microbiological research.
• Oral Dosage Forms: Used in the production of tablets and capsules for systemic antibacterial therapy.
• Ophthalmic Solutions: A component in the formulation of eye drops for treating bacterial conjunctivitis.
• Bulk Drug Substance: Supplied to compounding pharmacies and large-scale pharmaceutical manufacturers for further processing.

Basic Information

Product Name	Norfloxacinehydrochloride
CAS No.	68077-27-0
Molecular Formula	C16H19FN3O3 • HCl
Molecular Weight	365.80 g/mol
Synonyms	Norfloxacin Hydrochloride; Norfloxacin HCl; 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid hydrochloride; AM-715 Hydrochloride; MK-0366 Hydrochloride; Lexinor; Zoroxin; Chibroxin; Noroxin
EINECS	Contact for details

Quality Control

Our Norfloxacinehydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for assay and related substances, to ensure it meets high-purity pharmacopeial standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee supply reliability and regulatory compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to protect from moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.