Description

H-Val-Tyr-Pro-Oh is a high-purity tripeptide derivative, specifically the C-terminal carboxylic acid form of the sequence Valine-Tyrosine-Proline. This compound serves as a critical building block (intermediate) in advanced pharmaceutical research and peptide synthesis. It is primarily utilized by R&D scientists and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutic agents and biochemical tools.

Application

• Pharmaceutical Intermediate: A key precursor in the solid-phase or solution-phase synthesis of longer, biologically active peptide chains for drug discovery.
• Biochemical Research: Used as a standard or reference compound in proteomics, enzymology, and metabolic pathway studies.
• Peptide Library Construction: Essential for creating combinatorial peptide libraries used in high-throughput screening for drug leads.
• API Development: Serves as a fragment in the research and development of potential Active Pharmaceutical Ingredients (APIs) targeting various diseases.
• Cosmeceutical Ingredient: Investigated for use in advanced skincare formulations due to the potential bioactivity of peptide sequences.

Basic Information

Product Name	H-Val-Tyr-Pro-Oh
CAS No.	68076-97-1
Molecular Formula	C₁₉H₂₇N₃O₅
Molecular Weight	377.44 g/mol
Synonyms	Val-Tyr-Pro-OH; L-Valyl-L-tyrosyl-L-proline; VYP-OH; H-Val-Tyr-Pro-OH tripeptide; Valyl-tyrosyl-proline; N-(N-Valyl-L-tyrosyl)-L-proline; L-Val-L-Tyr-L-Pro-OH; 2-[(2S)-2-[[(2S)-2-amino-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our H-Val-Tyr-Pro-Oh is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications. We support development projects requiring standards aligned with GMP or research-grade guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Total)	≥ 99.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.