Description

4-(3-Fluorophenyl)Pyrimidine is a high-purity fluorinated pyrimidine derivative, a key heterocyclic building block prized for its role in advanced organic synthesis. This compound matters because it provides a versatile scaffold for introducing both fluorine and pyrimidine pharmacophores, enabling the development of novel compounds with tailored electronic and steric properties. It is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly those focused on medicinal chemistry, drug discovery, and the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrimidine core.
• Material Science: Serves as a precursor for organic electronic materials, such as ligands for OLEDs or charge-transport materials.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization to modulate potency, selectivity, and metabolic stability.
• Chemical Synthesis: Acts as a versatile reagent for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to create complex biaryl structures.
• Ligand Synthesis: Used to prepare specialized ligands for catalysis in asymmetric synthesis and transition metal complexes.

Basic Information

Product Name	4-(3-Fluorophenyl)Pyrimidine
CAS No.	68049-18-3
Molecular Formula	C10H7FN2
Molecular Weight	174.18 g/mol
Synonyms	3-Fluoro-4-pyrimidinylbenzene; 4-(3-Fluorophenyl)pyrimidine; 3-Fluorophenylpyrimidine; m-Fluorophenylpyrimidine; Pyrimidine, 4-(3-fluorophenyl)-; 4-(m-Fluorophenyl)pyrimidine
EINECS	Contact for details

Quality Control

Our 4-(3-Fluorophenyl)Pyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP-compliant production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.