Description

Isepamicinsulfate CAS NO 68000-78-2 is a high-purity aminoglycoside antibiotic sulfate salt, essential for pharmaceutical research and development. This compound is valued for its broad-spectrum antibacterial activity, particularly against Gram-negative bacteria, making it a critical intermediate in antimicrobial studies. It is primarily required by pharmaceutical manufacturers, research institutions, and biotechnology companies for the development of novel antibiotic formulations and clinical research.

Application

• Pharmaceutical Active Ingredient (API): Used as a key raw material in the formulation of injectable antibiotic drugs.
• Microbiological Research: Serves as a reference standard and active agent in studies of bacterial resistance mechanisms and efficacy testing.
• Veterinary Medicine: Employed in the development of treatments for bacterial infections in animals.
• Clinical Diagnostics: Utilized in laboratory settings for susceptibility testing and as a component in culture media for specific bacterial strains.
• Biochemical Synthesis: Acts as a starting material or intermediate in the synthetic pathways for more complex antimicrobial agents.

Basic Information

Product Name	Isepamicinsulfate
CAS No.	68000-78-2
Molecular Formula	C22H43N5O12 • xH2SO4
Molecular Weight	569.60 g/mol (for free base C22H43N5O12)
Synonyms	Isepamicin Sulfate; Isepamicin Sulphate; Sch 21420; 1-N-[(S)-4-Amino-2-hydroxybutyryl]-6'-N-methylgentamicin C1a sulfate; Antibiotic Sch 21420; 4'-Deoxy-6'-N-methylamikacin sulfate; (2S)-4-Amino-N-[(1R,2S,3S,4R,5S)-5-amino-4-{[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2-{[(2R,3R,4R,5R)-3,5-dihydroxy-5-methyl-4-(methylamino)oxan-2-yl]oxy}-3-hydroxycyclohexyl]-2-hydroxybutanamide sulfate
EINECS	Contact for details

Quality Control

Our Isepamicinsulfate is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing including HPLC for purity and assay, identification by IR and NMR, and stringent tests for related substances, residual solvents, and microbiological load. We provide full traceability and Certificates of Analysis (COA) are available upon request, ensuring compliance with relevant pharmaceutical guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC, anhydrous basis)	95.0% - 102.0%
Water Content (KF)	≤ 8.0 %
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
pH (1% solution)	3.5 - 5.5
Specific Rotation	+100° to +115°
Bacterial Endotoxins	< 0.5 EU/mg
Microbial Enumeration	Meets Ph. Eur. 2.6.12 / USP <61>

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.