Description

Pseudohirudin CAS NO 67995-65-7 is a potent and specific thrombin inhibitor, a recombinant protein derived from the medicinal leech. This compound is critical for advanced biochemical research and development, particularly in the study of blood coagulation pathways and thrombosis. It is primarily utilized by pharmaceutical R&D teams, diagnostic manufacturers, and academic institutions focused on cardiovascular and hematological sciences.

Application

• Biochemical Research: As a specific tool for studying thrombin's role in coagulation, inflammation, and cell signaling pathways.
• Pharmaceutical Development: Serves as a reference standard and key intermediate in the development of novel anticoagulant and antithrombotic therapies.
• Diagnostic Reagent Production: Used in the formulation of in-vitro diagnostic kits for assessing blood clotting function and thrombotic risk.
• Enzymology Studies: Employed in kinetic assays to measure thrombin activity and to screen for potential inhibitory compounds.
• Structural Biology: Aids in X-ray crystallography and NMR studies to elucidate the structure of thrombin-inhibitor complexes.

Basic Information

Product Name	Pseudohirudin
CAS No.	67995-65-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Recombinant Hirudin Variant 1; rHV1; Hirudin Variant 1; Hirudin (recombinant); Hirudin-1; Thrombin Inhibitor (recombinant); Anticoagulant Protein; Leech-derived Thrombin Inhibitor (recombinant)
EINECS	Contact for details

Quality Control

Our Pseudohirudin is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, SDS-PAGE for identity, and functional activity assays to ensure consistent biological potency. A comprehensive Certificate of Analysis (COA), detailing purity, activity, and endotoxin levels, is provided with every shipment to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Reconstituted solutions should be aliquoted and stored at -70°C to -80°C to prevent repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive).

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Biological Activity	≥ 12,000 ATU/mg
Endotoxin	< 10 EU/mg
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.