Description

Cyclo(Pro-Trp) CAS NO 67889-75-2 is a synthetic cyclic dipeptide, also known as a diketopiperazine (DKP), composed of proline and tryptophan. This compound is of significant interest in pharmaceutical research and development due to its role as a key structural motif and potential pharmacophore. It serves as a critical intermediate and building block for researchers and manufacturers in the life sciences sector.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block for the synthesis of more complex peptide-based drugs and bioactive molecules.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and as a scaffold for developing new therapeutic agents targeting various diseases.
• Peptidomimetics Development: Acts as a stable, conformationally restricted core for designing peptidomimetics that mimic natural peptides but with enhanced metabolic stability.
• Biochemical Tool Compound: Employed in biochemical assays and as a reference standard to study enzyme inhibition or receptor-ligand interactions.
• Academic & Industrial R&D: Utilized in universities and corporate R&D labs for exploratory research in organic synthesis and peptide chemistry.

Basic Information

Product Name	Cyclo(Pro-Trp)
CAS No.	67889-75-2
Molecular Formula	C16H17N3O2
Molecular Weight	283.33 g/mol
Synonyms	Cyclo(L-prolyl-L-tryptophyl); L-Prolyl-L-tryptophan anhydride; 3-(1H-Indol-3-ylmethyl)-6,7-diazabicyclo[3.3.0]octane-2,5-dione; Pro-Trp Diketopiperazine; Cyclo(Pro-Trp) DKP; c(Pro-Trp); L-Pro-L-Trp cyclic dipeptide; 2,5-Diketopiperazine-3-(3-indolylmethyl)-6-carboxylic acid (from L-Pro and L-Trp)
EINECS	Contact for details

Quality Control

Our Cyclo(Pro-Trp) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets high-purity standards suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.