Description

2,3,6-Trifluoroaniline is a versatile fluorinated aromatic amine building block of significant importance in advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers creating active pharmaceutical ingredients (APIs), crop protection agents, and specialty materials that require precise fluorine substitution to modulate biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where fluorine atoms enhance efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display and lighting technologies.
• Polymer & Resin Modifier: Incorporated into specialty polymers to improve chemical resistance, thermal stability, and surface properties.
• Dye & Pigment Manufacturing: Acts as an intermediate for producing high-performance, light-fast fluorinated dyes and pigments.
• Cross-Coupling Reactions: Utilized in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed reactions to introduce aniline functionalities into complex scaffolds.

Basic Information

Product Name	2,3,6-Trifluoroaniline
CAS No.	67815-56-9
Molecular Formula	C6H4F3N
Molecular Weight	147.10 g/mol
Synonyms	2,3,6-Trifluorobenzenamine; 1-Amino-2,3,6-trifluorobenzene; Benzenamine, 2,3,6-trifluoro-; 2,3,6-Trifluoro-phenylamine; 2,3,6-Trifluoroaniline (principal name); 2,3,6-F3C6H2NH2; Aniline, 2,3,6-trifluoro-
EINECS	Contact for details

Quality Control

Our 2,3,6-Trifluoroaniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.