Description

Fa-Gly-Nva-NH2 is a specialized synthetic peptide building block, specifically a protected tripeptide derivative. This high-purity intermediate is critical for researchers and manufacturers requiring precise molecular control in complex synthesis workflows. It is primarily utilized in pharmaceutical R&D, particularly in the development of novel peptide-based therapeutics and diagnostic agents.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected fragment for the efficient, sequential assembly of longer, complex peptide chains.
• Pharmaceutical Research: Serves as a crucial intermediate in the discovery and development of new peptide drugs targeting various diseases.
• Bioconjugation: Used to create peptide-protein or peptide-small molecule conjugates for targeted drug delivery systems.
• Structure-Activity Relationship (SAR) Studies: Enables medicinal chemists to systematically modify peptide sequences to optimize potency, selectivity, and stability.
• Biomimetic Material Development: Incorporated into synthetic polymers to impart bioactivity or specific molecular recognition properties.
• Chemical Biology Probes: Acts as a component in the synthesis of labeled peptides used to study biological pathways and protein interactions.

Basic Information

Product Name	Fa-Gly-Nva-NH2
CAS No.	67607-50-5
Molecular Formula	C₁₉H₂₈N₄O₄
Molecular Weight	376.45 g/mol
Synonyms	Fmoc-Gly-Nva-NH2; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]glycyl-L-norvalinamide; Fmoc-Gly-L-Nva-NH2; Nα-Fmoc-glycyl-L-norvalinamide; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-N-(2-amino-1-hydroxy-4-methylpentan-1-yl)acetamide; Fmoc-Gly-Norvaline-amide; Fmoc-Gly-Nva-amide; Protected Gly-Norvaline dipeptide amide
EINECS	Contact for details

Quality Control

Our Fa-Gly-Nva-NH2 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity. For long-term storage, consider desiccant and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.