Description

4-Bromo-2,6-Difluoroaniline is a halogenated aniline derivative that serves as a versatile and critical building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients and specialty agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific bromo and fluoro substituents into target molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring halogenated aromatic cores for bioactivity or metabolic stability.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and insecticides, where the difluoro and bromo groups can enhance compound efficacy and environmental profile.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Dye & Pigment Intermediate: Employed in the production of specialized dyes and pigments, where halogen atoms influence color fastness and spectral properties.
• Cross-Coupling Reactions: Acts as a substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions to form complex biaryl structures.
• Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating novel chemical entities.

Basic Information

Product Name	4-Bromo-2,6-Difluoroaniline
CAS No.	67567-26-4
Molecular Formula	C6H4BrF2N
Molecular Weight	208.00 g/mol
Synonyms	2,6-Difluoro-4-bromoaniline; 4-Bromo-2,6-difluorobenzenamine; 1-Amino-4-bromo-2,6-difluorobenzene; Benzenamine, 4-bromo-2,6-difluoro-; Aniline, 4-bromo-2,6-difluoro-; 4-Bromo-2,6-difluoro-phenylamine
EINECS	Contact for details

Quality Control

Our 4-Bromo-2,6-Difluoroaniline is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, GC, and NMR, to confirm identity and quantify impurities. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in the original packaging or amber glass until use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.