Description

4-Fluoro-3-(trifluoromethyl)benzyl alcohol is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both fluorine and a trifluoromethyl group, makes it a critical intermediate for introducing lipophilicity and metabolic stability into target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine motifs enhance biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance display technologies.
• Functional Polymer Monomer: Incorporated into specialty polymers to impart unique chemical resistance, low surface energy, and optical properties.
• Organic Electronic Materials: Employed in the development of materials for organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Research & Development: A valuable reagent for exploring new fluorination methodologies and constructing complex molecular architectures in academic and industrial labs.

Basic Information

Product Name	4-Fluoro-3-(trifluoromethyl)benzyl Alcohol
CAS No.	67515-61-1
Molecular Formula	C8H6F4O
Molecular Weight	194.13 g/mol
Synonyms	α,α,α-Trifluoro-4-fluoro-m-tolylmethanol; (4-Fluoro-3-(trifluoromethyl)phenyl)methanol; 3-(Trifluoromethyl)-4-fluorobenzyl alcohol; 4-Fluoro-α,α,α-trifluoro-m-tolylcarbinol; 1-(4-Fluoro-3-(trifluoromethyl)phenyl)methanol; 4-Fluoro-3-trifluoromethylbenzyl alcohol; 67515-61-1; 4-Fluoro-alpha,alpha,α-trifluoro-m-tolylcarbinol
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-(trifluoromethyl)benzyl alcohol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.