Description

H-Leu-Trp-Met-Arg-Oh is a synthetic tetrapeptide sequence composed of leucine, tryptophan, methionine, and arginine. This compound is of significant interest in biochemical and pharmaceutical research for its potential role in studying peptide structure-activity relationships and enzyme-substrate interactions. It serves as a critical building block and reference standard for researchers and manufacturers in the life sciences sector, particularly those focused on peptide synthesis, proteomics, and drug discovery.

Application

• Pharmaceutical Research & Development: Used as a reference standard, intermediate, or model compound in the development of novel therapeutic peptides and peptidomimetics.
• Biochemical Studies: Employed in enzymatic assays and studies of protease specificity, protein-protein interactions, and signal transduction pathways.
• Peptide Synthesis: Serves as a key building block for the solid-phase or solution-phase synthesis of longer, more complex peptide chains.
• Proteomics & Mass Spectrometry: Utilized as a calibration standard or a defined sequence for method development in analytical techniques like HPLC-MS.
• Academic Research: Applied in university and institutional labs for fundamental research into peptide chemistry, folding, and biological activity.

Basic Information

Product Name	H-Leu-Trp-Met-Arg-Oh
CAS No.	67368-23-4
Molecular Formula	C30H46N8O6S
Molecular Weight	646.81 g/mol
Synonyms	L-Leucyl-L-tryptophyl-L-methionyl-L-arginine; Leu-Trp-Met-Arg; H-Leu-Trp-Met-Arg-OH tetrapeptide; LWMR; Tetrapeptide LWMR; Arg-Met-Trp-Leu; L-Arginyl-L-methionyl-L-tryptophyl-L-leucine; (Sequence: Leu-Trp-Met-Arg)
EINECS	Contact for details

Quality Control

Our H-Leu-Trp-Met-Arg-Oh is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research-grade peptides, ensuring reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider desiccated conditions at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to theoretical mass
Purity (HPLC)	≥ 95.0%
Assay (HPLC)	≥ 97.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.