Description

H-Pro-Val-Gly-Oh is a synthetic tripeptide derivative, specifically a protected peptide fragment. This compound is a crucial building block in solid-phase peptide synthesis (SPPS), enabling the controlled assembly of longer, more complex peptide sequences. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Pharmaceutical Intermediate: Key raw material for the synthesis of longer therapeutic peptide chains targeting various diseases.
• Biochemical Research: Used as a standard or building block in proteomics, enzymology, and structure-activity relationship (SAR) studies.
• Peptide Library Construction: Essential component in combinatorial chemistry for generating diverse peptide libraries for high-throughput screening.
• Custom Peptide Synthesis: Serves as a starting material for contract research and manufacturing organizations (CROs/CMOs) producing custom peptides for clients.
• Academic Research: Employed in university and institutional labs for fundamental research in peptide chemistry and molecular biology.

Basic Information

Product Name	H-Pro-Val-Gly-Oh
CAS No.	67341-70-2
Molecular Formula	C13H21N3O4
Molecular Weight	283.33 g/mol
Synonyms	L-Prolyl-L-valylglycine; Pro-Val-Gly; H-Pro-Val-Gly-OH; Pro-Val-Gly-OH; L-Pro-L-Val-Gly; (S)-2-((S)-2-((S)-Pyrrolidine-2-carboxamido)-3-methylbutanamido)acetic acid; N-[(2S)-1-[[(2S)-2-[[(2S)-Pyrrolidin-2-yl]formamido]-3-methylbutanoyl]amino]-2-oxoethyl]formamide; Peptide Fragment Pro-Val-Gly
EINECS	Contact for details

Quality Control

Our H-Pro-Val-Gly-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via mass spectrometry and IR spectroscopy. We provide Certificates of Analysis (COA) with detailed specifications for trace metals, residual solvents, and related substances, ensuring compliance with research and cGMP-grade standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.