Description

Acetamide, 2,2,2-Trifluoro-n-[4-(Trifluoromethyl)Phenyl]- is a specialized fluorinated acetamide derivative, a high-value intermediate prized for its unique chemical structure. Its core value lies in introducing multiple trifluoromethyl groups, which are critical for modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to develop novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, inflammatory diseases, and oncology.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the fluorine atoms contribute to improved biological activity and environmental persistence profiles.
• Material Science Research: Serves as a precursor for developing specialty polymers, liquid crystals, or organic electronic materials that benefit from fluorine's unique electronic properties.
• Chemical Biology Probe Development: Employed in creating labeled compounds or molecular probes for studying biochemical pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for fine chemical manufacturers offering bespoke synthesis services to the life sciences sector.

Basic Information

Product Name	Acetamide, 2,2,2-Trifluoro-n-[4-(Trifluoromethyl)Phenyl]-
CAS No.	67319-83-9
Molecular Formula	C10H7F6NO
Molecular Weight	271.16 g/mol
Synonyms	2,2,2-Trifluoro-N-[4-(trifluoromethyl)phenyl]acetamide; N-[4-(Trifluoromethyl)phenyl]-2,2,2-trifluoroacetamide; α,α,α-Trifluoro-N-[α,α,α-trifluoro-p-tolyl]acetamide; 4'-(Trifluoromethyl)-2,2,2-trifluoroacetanilide; p-Trifluoromethyl-α,α,α-trifluoroacetanilide; TFMP-TFA (common abbreviation)
EINECS	Contact for details

Quality Control

Every batch of Acetamide, 2,2,2-Trifluoro-n-[4-(Trifluoromethyl)Phenyl]- is produced under strict quality management protocols. We ensure compliance with relevant industry standards for fine chemical intermediates. Comprehensive analytical testing, including HPLC, NMR, and GC-MS, is performed to verify identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.