Description

2(1H)-Pyrimidinethione, 4-Amino-5-Fluoro- (9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique fluorinated pyrimidine-thione core enables precise molecular modifications. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the synthesis of new therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel fluorinated pyrimidine-based drug candidates, including potential kinase inhibitors and antiviral agents.
• Agrochemical Research: Used in the development of next-generation herbicides and fungicides, leveraging the bioactivity of the fluorinated heterocycle.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization, enabling the creation of complex molecular libraries for high-throughput screening.
• Material Science: Investigated for the preparation of specialty chemicals and functional materials with specific electronic or binding properties.

Basic Information

Product Name	2(1H)-Pyrimidinethione, 4-Amino-5-Fluoro- (9Ci)
CAS No.	67316-49-8
Molecular Formula	C4H4FN3S
Molecular Weight	145.16 g/mol
Synonyms	4-Amino-5-fluoro-2(1H)-pyrimidinethione; 4-Amino-5-fluoropyrimidine-2-thiol; 5-Fluoro-4-aminopyrimidine-2-thiol; 4-Amino-5-fluoro-2-mercaptopyrimidine; 2-Mercapto-4-amino-5-fluoropyrimidine; 4-Amino-5-fluoro-2-pyrimidinethiol; 4-Amino-5-fluoro-1H-pyrimidine-2-thione
EINECS	Contact for details

Quality Control

Our production of 4-Amino-5-fluoro-2(1H)-pyrimidinethione adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the exacting standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Yellow to light brown powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.