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o-[2-(Acetylamino)-2-Deoxy-α-D-Galactopyranosyl]-L-Threonine CAS NO 67315-18-8


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CAS No.:67315-18-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

o-[2-(Acetylamino)-2-Deoxy-α-D-Galactopyranosyl]-L-Threonine is a specialized glycosylated amino acid derivative, serving as a crucial building block in advanced biochemical synthesis. This compound is valued for its role in constructing complex glycopeptides and glycoproteins, which are essential for studying and modulating biological recognition processes. It is primarily sought by research institutions and pharmaceutical developers working in glycobiology, drug discovery, and the development of novel therapeutic agents, including vaccines and targeted biologics.

Application

  • Glycopeptide Synthesis: A key intermediate for the solid-phase or solution-phase synthesis of biologically active glycopeptides.
  • Pharmaceutical Research: Used in the discovery and development of new drug candidates, particularly in oncology and immunology.
  • Bioconjugation: Employed to create chemically defined protein conjugates for diagnostic and therapeutic applications.
  • Enzyme Substrate Studies: Serves as a substrate or inhibitor in studies of glycosyltransferases and other carbohydrate-processing enzymes.
  • Standards and Reference Materials: Used as a high-purity analytical standard in quality control and metabolic pathway research.
  • Chemical Biology Probes: Incorporated into molecular probes to investigate cell-surface interactions and signaling pathways.

Basic Information

Item Details
Product Name o-[2-(Acetylamino)-2-Deoxy-α-D-Galactopyranosyl]-L-Threonine
CAS No. 67315-18-8
Molecular Formula C13H22N2O9
Molecular Weight 350.33 g/mol
Synonyms N-Acetyl-α-D-galactosaminyl-L-threonine; GalNAc-α-Thr; O-(2-Acetamido-2-deoxy-α-D-galactopyranosyl)-L-threonine; α-GalNAc-Thr; Tn antigen amino acid derivative; Threonine linked N-acetyl-α-D-galactosamine; Acetylgalactosaminylthreonine; O-α-D-GalNAc-L-Thr
EINECS Contact for details

Quality Control

Our o-[2-(Acetylamino)-2-Deoxy-α-D-Galactopyranosyl]-L-Threonine is produced under stringent conditions to ensure high chemical purity and batch-to-batch consistency, suitable for sensitive research applications. Quality is verified through a comprehensive suite of analytical techniques including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each batch, confirming identity, purity, and conformity to specified standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 5.0%
Specific Rotation Contact for details
Heavy Metals < 20 ppm
Residual Solvents (GC) Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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