Description

5,9,10,14B-Tetrahydro-5,10-Dimethylisoquino[2,1-D][1,4]Benzodiazepin-6(7H)-One is a high-purity, complex heterocyclic organic compound with a fused benzodiazepine-isoquinoline structure. This specialized chemical serves as a critical pharmaceutical intermediate and a valuable scaffold in medicinal chemistry research for developing novel therapeutic agents. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of advanced active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those targeting the central nervous system.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Employed in studies investigating ligand-receptor interactions, particularly with benzodiazepine receptor sites.
• Process Development: Utilized in the optimization and scale-up of synthetic routes for advanced pharmaceutical manufacturing.

Basic Information

Product Name	5,9,10,14B-Tetrahydro-5,10-Dimethylisoquino[2,1-D][1,4]Benzodiazepin-6(7H)-One
CAS No.	67239-21-8
Molecular Formula	C19H18N2O
Molecular Weight	290.36 g/mol
Synonyms	5,10-Dimethyl-5,9,10,14b-tetrahydroisoquino[2,1-d][1,4]benzodiazepin-6(7H)-one; 5,10-Dimethyl-6,7-dihydro-5H-isoquino[2,1-d][1,4]benzodiazepin-6-one; 67239-21-8; Isoquino[2,1-d][1,4]benzodiazepin-6(7H)-one, 5,9,10,14b-tetrahydro-5,10-dimethyl-
EINECS	Contact for details

Quality Control

Our production of 5,9,10,14B-Tetrahydro-5,10-Dimethylisoquino[2,1-D][1,4]Benzodiazepin-6(7H)-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials are subjected to comprehensive analytical characterization using techniques such as HPLC, NMR, and MS. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment, supporting compliance in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.