Description

tert-Butyloxycarbonyl-Lysyl-Alanyl-Alanine is a protected tripeptide derivative, widely utilized as a key building block in solid-phase peptide synthesis (SPPS). Its primary value lies in providing a precisely defined amino acid sequence with orthogonal protecting groups, enabling the controlled elongation of complex peptide chains. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors who are developing therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Pharmaceutical Intermediates: Critical building block for the synthesis of novel therapeutic peptides and peptidomimetics.
• Biochemical Research: Used in the study of peptide structure-activity relationships (SAR) and enzyme-substrate interactions.
• Solid-Phase Peptide Synthesis (SPPS): A fundamental reagent for the controlled, sequential assembly of custom peptide sequences on resin supports.
• Antigen Synthesis: Employed in the production of peptide antigens for antibody development and immunological assays.
• Protease Substrate Analogues: Serves as a substrate or inhibitor model in enzymatic studies for drug discovery.
• Cosmetic Peptide Development: A precursor in the synthesis of bioactive peptides for advanced skincare formulations.

Basic Information

Product Name	tert-Butyloxycarbonyl-Lysyl-Alanyl-Alanine
CAS No.	67223-73-8
Molecular Formula	C20H36N4O7
Molecular Weight	444.53 g/mol
Synonyms	Boc-Lys-Ala-Ala-OH; Boc-Lys-Ala-Ala; N-α-Boc-L-lysyl-L-alanyl-L-alanine; (2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[(2-methylpropan-2-yl)oxycarbonylamino]hexanoyl]amino]propanoyl]amino]propanoic acid; Boc-Lys(Boc)-Ala-Ala-OH (if side-chain protected); H-Lys(Boc)-Ala-Ala-OH Boc-form; Nα-Boc-L-lysyl-L-alanyl-L-alanine; Peptide Synthesis Reagent 67223-73-8
EINECS	Contact for details

Quality Control

Our tert-Butyloxycarbonyl-Lysyl-Alanyl-Alanine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS and NMR for structural confirmation, and chiral purity analysis to ensure identity, strength, and composition. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting compliance with cGMP and research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.