Description

H-Ala-Ala-Tyr-Oh is a high-purity tripeptide derivative consisting of two alanine residues and a tyrosine residue with a free carboxylic acid terminus. This compound serves as a critical building block and reference standard in advanced biochemical research and pharmaceutical development. It is essential for researchers and manufacturers in the fields of peptide synthesis, proteomics, and medicinal chemistry who require precise and reliable intermediates for creating complex molecular structures.

Application

• Peptide Synthesis Intermediate: A key raw material for the solid-phase or solution-phase synthesis of longer, biologically active peptide sequences.
• Biochemical Research: Used as a substrate or standard in enzymatic studies, particularly for investigating protease specificity and kinetics.
• Pharmaceutical Development: Serves as a core fragment in the design and development of novel therapeutic peptides and peptidomimetics.
• Proteomics & Mass Spectrometry: Employed as a calibration standard or model compound in mass spectrometry for method development and instrument calibration.
• Academic Research: Utilized in university and institutional labs for teaching and fundamental research in organic chemistry and peptide science.
• Reference Standard: Provides a high-purity benchmark for quality control and analytical method validation in peptide production.

Basic Information

Product Name	H-Ala-Ala-Tyr-Oh
CAS No.	67131-52-6
Molecular Formula	C15H21N3O5
Molecular Weight	323.35 g/mol
Synonyms	Ala-Ala-Tyr; AAY; H-Ala-Ala-Tyr-OH; L-Alanyl-L-alanyl-L-tyrosine; Tripeptide AAY; N-(N-L-Alanyl-L-alanyl)-L-tyrosine; 2-[[2-[(2-Amino-1-oxopropyl)amino]-1-oxopropyl]amino]-3-(4-hydroxyphenyl)propanoic acid
EINECS	Contact for details

Quality Control

Our H-Ala-Ala-Tyr-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the stringent requirements for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Assay	≥ 97.0% (on dried basis)
Optical Rotation	-20° to -30° (c=1 in 1% Acetic Acid)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.