Description

6-Amino-5-(2-Chloro-Acetyl)-1,3-Dimethyl-1H-Pyrimidine-2,4-Dione is a high-value, multi-functional heterocyclic building block with significant synthetic utility. This compound matters as a key intermediate in the synthesis of complex pharmaceutical molecules, particularly in the development of novel therapeutic agents. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for advanced organic synthesis and process development.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of xanthine-derived drug candidates, including potential adenosine receptor antagonists and phosphodiesterase (PDE) inhibitors.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its reactive chloroacetyl and amino groups for further functionalization.
• Fine Chemical Building Block: Serves as a versatile scaffold for constructing complex heterocyclic compounds in academic and industrial research settings.
• Biochemical Research: Employed in the study of enzyme inhibition and as a tool compound for probing biological pathways related to purine metabolism.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic materials with specific electronic properties.

Basic Information

Product Name	6-Amino-5-(2-Chloro-Acetyl)-1,3-Dimethyl-1H-Pyrimidine-2,4-Dione
CAS No.	67130-66-9
Molecular Formula	C8H10ClN3O3
Molecular Weight	231.64 g/mol
Synonyms	6-Amino-5-(chloroacetyl)-1,3-dimethyluracil; 5-(Chloroacetyl)-6-amino-1,3-dimethyluracil; 1,3-Dimethyl-6-amino-5-chloroacetyluracil; 6-Amino-1,3-dimethyl-5-(2-chloroacetyl)pyrimidine-2,4(1H,3H)-dione; 6-Amino-5-(2-chloroacetyl)-1,3-dimethyluracil; 5-(2-Chloroacetyl)-6-amino-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione; 67130-66-9; 6-Amino-5-chloroacetyl-1,3-dimethyluracil
EINECS	Contact for details

Quality Control

Our 6-Amino-5-(2-Chloro-Acetyl)-1,3-Dimethyl-1H-Pyrimidine-2,4-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee reliable quality for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive and hygroscopic; therefore, containers should be kept sealed under an inert atmosphere when not in use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.