Description

H-D-Ala-Leu-Oh CAS NO 67113-60-4 is a high-purity, protected dipeptide building block used in advanced organic synthesis and peptide research. This compound is essential for constructing specific peptide sequences with defined stereochemistry, enabling the development of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and academic research laboratories focused on peptide-based drug discovery and development.

Application

• Pharmaceutical Intermediates: A key chiral building block for the solid-phase and solution-phase synthesis of therapeutic peptides.
• Peptide Drug Discovery: Used in research to create and screen novel peptide libraries for biological activity.
• Bioconjugation: Serves as a linker or spacer molecule in the development of peptide-drug conjugates and other bioconjugates.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies and proteomics research.
• Custom Peptide Synthesis: A critical raw material for CROs and CDMOs offering bespoke peptide manufacturing services.

Basic Information

Product Name	H-D-Ala-Leu-Oh
CAS No.	67113-60-4
Molecular Formula	C9H18N2O3
Molecular Weight	202.25 g/mol
Synonyms	H-D-Ala-Leu-OH; D-Alanyl-L-leucine; (R)-2-((S)-2-Aminopropanamido)-4-methylpentanoic acid; D-Ala-L-Leu; Ala-Leu; Alanine-Leucine dipeptide; Boc-D-Ala-L-Leu-OH (protected form precursor); D-Alanine-L-Leucine
EINECS	Contact for details

Quality Control

Our H-D-Ala-Leu-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral integrity, and impurity profiles. We adhere to cGMP guidelines for the production of advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.