Description

5-(Ethylthiomethyl)-5-(1-Methylbutyl)-2-Sodiooxy-4,6(1H,5H)-Pyrimidinedione is a specialized sodium salt derivative of a barbiturate analog, representing a high-value intermediate in advanced organic synthesis. This compound is critical for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the fine chemical and active pharmaceutical ingredient (API) manufacturing sectors for creating novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel barbiturate and thiobarbiturate analogs for central nervous system (CNS) drug discovery.
• Chemical Research: Used in academic and industrial laboratories for studying structure-activity relationships (SAR) and developing new synthetic methodologies.
• Fine Chemical Synthesis: Serves as a precursor for creating complex heterocyclic compounds with potential biological activity.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for target molecules in pre-clinical and clinical development.

Basic Information

Product Name	5-(Ethylthiomethyl)-5-(1-Methylbutyl)-2-Sodiooxy-4,6(1H,5H)-Pyrimidinedione
CAS No.	67051-16-5
Molecular Formula	C12H17N2NaO3S
Molecular Weight	292.33 g/mol
Synonyms	Sodium 5-(Ethylthiomethyl)-5-(1-methylbutyl)barbiturate; 5-(Ethylthiomethyl)-5-(1-methylbutyl)-2,4,6(1H,3H,5H)-pyrimidinetrione sodium salt; 5-(Ethylthiomethyl)-5-(1-methylpentyl)barbituric acid sodium derivative; Barbituric acid, 5-(ethylthiomethyl)-5-(1-methylbutyl)-, sodium salt; 67051-16-5; Sodium 5-(1-methylbutyl)-5-(ethylthiomethyl)barbiturate
EINECS	Contact for details

Quality Control

Our production of 5-(Ethylthiomethyl)-5-(1-Methylbutyl)-2-Sodiooxy-4,6(1H,5H)-Pyrimidinedione adheres to stringent quality management protocols to ensure batch-to-batch consistency and purity for research applications. All materials are characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or storing under an inert atmosphere such as nitrogen or argon to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.