Description

5-Ethyl-5-(2-Phenoxyethyl)-2-Sodiooxy-4,6(1H,5H)-Pyrimidinedione is a specialized sodium salt derivative of a barbiturate-class heterocyclic compound, serving as a critical synthetic intermediate and active pharmaceutical ingredient (API) precursor. Its value lies in its precise chemical structure, which is engineered for high reactivity and purity in advanced organic synthesis. This compound is essential for research and manufacturing in the pharmaceutical industry, particularly for developing central nervous system (CNS) agents and other fine chemicals.

Application

• Pharmaceutical Intermediate: Primary use as a key building block in the synthesis of barbiturate and thiobarbiturate-based active pharmaceutical ingredients (APIs).
• CNS Drug Research: Critical precursor in the research and development of sedative, hypnotic, and anticonvulsant pharmaceutical compounds.
• Fine Chemical Synthesis: Used in custom synthesis and process development for complex organic molecules requiring the pyrimidinedione core structure.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory testing in pharmaceutical laboratories.
• Academic & Industrial R&D: Employed in research institutions and corporate R&D departments for exploring new chemical entities and reaction methodologies.

Basic Information

Product Name	5-Ethyl-5-(2-Phenoxyethyl)-2-Sodiooxy-4,6(1H,5H)-Pyrimidinedione
CAS No.	67050-88-8
Molecular Formula	C₁₄H₁₅N₂NaO₄
Molecular Weight	298.27 g/mol
Synonyms	5-Ethyl-5-(2-phenoxyethyl)barbituric acid sodium salt; Sodium 5-ethyl-5-(2-phenoxyethyl)barbiturate; Phenobarbital sodium derivative; 5-Ethyl-5-(2-phenoxyethyl)-2,4,6(1H,3H,5H)-pyrimidinetrione sodium salt; Sodium 5-ethyl-5-(phenoxyethyl)barbiturate; Barbituric acid, 5-ethyl-5-(2-phenoxyethyl)-, sodium salt; Sodiooxy derivative of 5-ethyl-5-(phenoxyethyl)barbituric acid
EINECS	Contact for details

Quality Control

Our 5-Ethyl-5-(2-Phenoxyethyl)-2-Sodiooxy-4,6(1H,5H)-Pyrimidinedione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC for assay and purity, residual solvent analysis, and identification by FT-IR and NMR to ensure compliance with stringent specifications. Certificates of Analysis (COA) documenting all test results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.