Description

5-sec-Butyl-5-(Ethylthiomethyl)-2-Sodiothio-4,6(1H,5H)-Pyrimidinedione is a specialized thiobarbiturate derivative, a key synthetic intermediate in the production of high-value pharmaceuticals. Its primary commercial value lies in its role as a precursor for the synthesis of potent barbiturate and thiobarbiturate-based active pharmaceutical ingredients (APIs). This compound is essential for manufacturers in the pharmaceutical and fine chemical industries requiring a reliable, high-purity building block for complex organic synthesis.

Application

• Pharmaceutical Intermediate: Critical precursor in the synthesis of barbiturate and thiobarbiturate-based sedative, hypnotic, and anesthetic APIs.
• Fine Chemical Synthesis: Serves as a versatile building block for creating complex heterocyclic compounds in research and development.
• Chemical Research: Used in academic and industrial R&D for studying structure-activity relationships (SAR) of central nervous system (CNS) agents.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	5-sec-Butyl-5-(Ethylthiomethyl)-2-Sodiothio-4,6(1H,5H)-Pyrimidinedione
CAS No.	67050-34-4
Molecular Formula	C11H17N2NaO2S2
Molecular Weight	304.38 g/mol
Synonyms	5-(1-Methylpropyl)-5-[(ethylthio)methyl]-2-thioxo-2,3-dihydro-4,6(1H,5H)-pyrimidinedione sodium salt; Sodium 5-sec-butyl-5-(ethylthiomethyl)-2-thiobarbiturate; 2-Thiobarbituric acid, 5-(1-methylpropyl)-5-[(ethylthio)methyl]-, sodium salt; Thiobarbiturate derivative sodium salt; BAY a 1040 intermediate; Secbutobarbital thiomethyl analog sodium salt
EINECS	Contact for details

Quality Control

Our 5-sec-Butyl-5-(Ethylthiomethyl)-2-Sodiothio-4,6(1H,5H)-Pyrimidinedione is manufactured under strict quality management systems. The product undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency suitable for pharmaceutical synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.