Description

5-sec-Butyl-5-(Ethylthiomethyl)-2-Sodiooxy-4,6(1H,5H)-Pyrimidinedione is a specialized sodium salt derivative of a barbituric acid analog, serving as a critical synthetic intermediate in advanced organic synthesis. Its value lies in providing a reactive, protected nucleophile for constructing complex heterocyclic frameworks, particularly in pharmaceutical research and development. This compound is essential for chemical manufacturers and R&D laboratories focused on developing novel active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals requiring precise molecular architecture.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel barbiturate and thiobarbiturate analogs for central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the pyrimidinedione core contributes to biological activity.
• Chemical Research & Development: Serves as a versatile precursor for creating libraries of heterocyclic compounds in medicinal and combinatorial chemistry.
• Fine Chemical Manufacturing: Employed in custom synthesis and contract manufacturing for producing high-value, low-volume specialty chemicals.
• Material Science Precursor: Potential use in developing organic electronic materials or metal-organic frameworks (MOFs) due to its functionalized structure.

Basic Information

Item	Details
Product Name	5-sec-Butyl-5-(Ethylthiomethyl)-2-Sodiooxy-4,6(1H,5H)-Pyrimidinedione
CAS No.	67050-32-2
Molecular Formula	C11H17N2NaO3S
Molecular Weight	280.32 g/mol
Synonyms	5-(1-Methylpropyl)-5-[(ethylthio)methyl]-2-sodiooxy-4,6-pyrimidinedione; Sodium 5-sec-butyl-5-(ethylthiomethyl)barbiturate; 2-Sodiooxy-5-sec-butyl-5-(ethylthiomethyl)-4,6(1H,5H)-pyrimidinedione; 5-sec-Butyl-5-(ethylthiomethyl)barbituric acid sodium salt; Barbituric acid, 5-(1-methylpropyl)-5-[(ethylthio)methyl]-, sodium salt; CAS 67050-32-2
EINECS	Contact for details

Quality Control

Our production of 5-sec-Butyl-5-(Ethylthiomethyl)-2-Sodiooxy-4,6(1H,5H)-Pyrimidinedione adheres to stringent quality management systems to ensure batch-to-batch consistency and reliability for your synthetic processes. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.