Description

Meclonazepam CAS NO 67027-56-9 is a benzodiazepine derivative of significant interest in pharmaceutical research and development. This compound serves as a crucial intermediate for the synthesis of novel therapeutic agents targeting the central nervous system. It is primarily utilized by research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in the development of anxiolytic and sedative-hypnotic medications.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of advanced benzodiazepine-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in preclinical and clinical research to study structure-activity relationships (SAR) and develop new CNS-targeting drugs.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.
• Chemical Synthesis: Employed in organic synthesis for the preparation of novel chemical entities with potential pharmacological activity.

Basic Information

Product Name	Meclonazepam
CAS No.	67027-56-9
Molecular Formula	C16H12ClN3O3
Molecular Weight	329.74 g/mol
Synonyms	Meclonazepam; 5-(2-Chlorophenyl)-1,3-dihydro-3-methyl-7-nitro-2H-1,4-benzodiazepin-2-one; Ro 05-4556; 3-Methylclonazepam; 3-Methyl-7-nitro-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one
EINECS	Contact for details

Quality Control

Our Meclonazepam is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identification, assay, and impurity profiling via HPLC, to meet the stringent requirements of pharmaceutical research. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.