Description

Diethyl [[[3-(4,7-Dihydro-7-Oxo-1H-1,2,3-Triazolo[4,5-D]Pyrimidin-5-Yl)-4-Propoxyphenyl]Amino]Methylene]Malonate is a sophisticated heterocyclic organic compound that serves as a critical advanced pharmaceutical intermediate (API intermediate) and a versatile building block in organic synthesis. Its complex molecular architecture, featuring fused triazolopyrimidine and malonate ester functionalities, makes it invaluable for constructing novel chemical entities with targeted biological activity. This high-purity compound is essential for research and development chemists in the pharmaceutical and agrochemical sectors, where it is used to develop new drug candidates and active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or other enzyme-related pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or plant growth regulators due to its heterocyclic core.
• Organic Synthesis Reagent: Serves as a versatile precursor for constructing complex heterocyclic systems in medicinal and combinatorial chemistry.
• Biochemical Probe Development: Utilized in academic and industrial research to create molecular probes for studying biological processes and target validation.
• Material Science Research: Potential intermediate for the synthesis of specialty chemicals or functional materials with specific electronic properties.

Basic Information

Product Name	Diethyl [[[3-(4,7-Dihydro-7-Oxo-1H-1,2,3-Triazolo[4,5-D]Pyrimidin-5-Yl)-4-Propoxyphenyl]Amino]Methylene]Malonate
CAS No.	66975-54-0
Molecular Formula	C22H24N6O5
Molecular Weight	452.47 g/mol
Synonyms	Diethyl (2Z)-2-({[3-(4,7-dihydro-7-oxo-1H-1,2,3-triazolo[4,5-d]pyrimidin-5-yl)-4-propoxyphenyl]amino}methylene)propanedioate; 5-[2-Propoxy-5-[[(ethoxycarbonyl)acetyl]iminomethyl]phenyl]-1,2,3-triazolo[4,5-d]pyrimidin-7-one; Propanedioic acid, [[[3-(4,7-dihydro-7-oxo-1H-1,2,3-triazolo[4,5-d]pyrimidin-5-yl)-4-propoxyphenyl]amino]methylene]-, diethyl ester; CAS 66975-54-0; 1H-1,2,3-Triazolo[4,5-d]pyrimidin-7(6H)-one, 5-[2-propoxy-5-[[(ethoxycarbonyl)acetyl]iminomethyl]phenyl]-; Diethyl [[[3-(4,7-Dihydro-7-Oxo-1H-1,2,3-Triazolo[4,5-D]Pyrimidin-5-Yl)-4-Propoxyphenyl]Amino]Methylene]Malonate
EINECS	Contact for details

Quality Control

Our production of Diethyl [[[3-(4,7-Dihydro-7-Oxo-1H-1,2,3-Triazolo[4,5-D]Pyrimidin-5-Yl)-4-Propoxyphenyl]Amino]Methylene]Malonate adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to cGMP (current Good Manufacturing Practice) standards ensures a reliable supply of this high-value intermediate for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and/or hygroscopic; prolonged exposure to light, moisture, or extreme temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.