Description

5-Ethyl-5-(1-Naphtylmethyl)-2,4,6(1H,3H,5H)-Pyrimidinetrione is a specialized heterocyclic organic compound belonging to the barbiturate family, characterized by its unique naphthylmethyl substitution. This structural feature makes it a valuable key intermediate in advanced organic synthesis, particularly for developing novel pharmacologically active molecules. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers for applications in medicinal chemistry and the production of high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the research and synthesis of new barbiturate-derived compounds with potential central nervous system (CNS) activity.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore and modify pharmacological profiles for drug discovery programs.
• Fine Chemical Synthesis: Acts as a precursor in the multi-step synthesis of complex organic molecules for academic and industrial research.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and compound identification.
• Biochemical Research: Potential application in studying enzyme interactions or as a ligand in biochemical assays due to its specific heterocyclic structure.

Basic Information

Product Name	5-Ethyl-5-(1-Naphtylmethyl)-2,4,6(1H,3H,5H)-Pyrimidinetrione
CAS No.	66969-01-5
Molecular Formula	C₁₇H₁₆N₂O₃
Molecular Weight	296.32 g/mol
Synonyms	5-Ethyl-5-(naphthalen-1-ylmethyl)pyrimidine-2,4,6(1H,3H,5H)-trione; 5-Ethyl-5-(1-naphthylmethyl)barbituric acid; 1-Naphthylmethyl-5-ethylbarbituric acid; 5-(1-Naphthylmethyl)-5-ethylbarbituric acid; 5-Ethyl-5-(1-naphthylmethyl)-2,4,6-trioxohexahydropyrimidine; Naphthylmethyl ethyl barbiturate
EINECS	Contact for details

Quality Control

Our 5-Ethyl-5-(1-Naphtylmethyl)-2,4,6(1H,3H,5H)-Pyrimidinetrione is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing key parameters such as assay and impurity profiles. Our quality systems are designed to meet the stringent requirements of pharmaceutical R&D and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.