Description

5-Ethyl-5-[(1-Methylbutyl)Thiomethyl]-2-Sodiooxy-4,6(1H,5H)-Pyrimidinedione is a specialized thiobarbiturate derivative, a key intermediate in the synthesis of advanced pharmaceutical compounds. Its value lies in its precise molecular structure, which is critical for developing central nervous system (CNS) acting drugs and other fine chemicals. This product is essential for research institutions, pharmaceutical development laboratories, and manufacturers requiring high-purity building blocks for active pharmaceutical ingredient (API) synthesis.

Application

• Pharmaceutical Intermediate: Primary use as a crucial building block in the synthesis of thiobarbiturate-based active pharmaceutical ingredients (APIs).
• CNS Drug Research: Serves as a key precursor in the research and development of sedative, hypnotic, and anesthetic compounds targeting the central nervous system.
• Fine Chemical Synthesis: Used in advanced organic synthesis to create complex heterocyclic compounds for medicinal chemistry applications.
• Reference Standard: Can be utilized as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Employed in studies investigating the structure-activity relationships of barbiturate analogs.

Basic Information

Product Name	5-Ethyl-5-[(1-Methylbutyl)Thiomethyl]-2-Sodiooxy-4,6(1H,5H)-Pyrimidinedione
CAS No.	66968-77-2
Molecular Formula	C₁₂H₁₇N₂NaO₃S
Molecular Weight	292.33 g/mol
Synonyms	5-Ethyl-5-[(1-methylbutyl)thiomethyl]barbituric acid sodium salt; Sodium 5-ethyl-5-[(1-methylbutyl)thiomethyl]barbiturate; Thiomethylbarbiturate sodium derivative; 2-Thiobarbituric acid derivative, sodium salt; 5-Ethyl-5-(1-methylbutylthiomethyl)barbituric acid sodium salt; NSC 113927; BRN 4779637
EINECS	Contact for details

Quality Control

Our 5-Ethyl-5-[(1-Methylbutyl)Thiomethyl]-2-Sodiooxy-4,6(1H,5H)-Pyrimidinedione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical intermediate use. Certificates of Analysis (COA) detailing all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.