Description

5-Ethyl-5-(Isopropylthiomethyl)-1-Methyl-2-Sodiooxy-4,6(1H,5H)-Pyrimidinedione is a specialized sodium salt derivative of a barbiturate analog, representing a high-value intermediate in advanced pharmaceutical synthesis. This compound matters for its role as a critical building block in the development of active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. Pharmaceutical manufacturers and advanced R&D facilities require this high-purity intermediate to ensure the efficacy and consistency of their final drug products.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of barbiturate-derived active pharmaceutical ingredients (APIs) and other therapeutic agents.
• Central Nervous System (CNS) Drug Research: Used in R&D for developing new sedative, hypnotic, or anticonvulsant medications.
• Chemical Synthesis Building Block: Employed in organic synthesis to introduce the thiomethyl-isopropyl functional group into complex molecular architectures.
• Reference Standard: Serves as an analytical standard for quality control and regulatory testing in pharmaceutical manufacturing.
• Process Chemistry: Utilized in scale-up and optimization of synthetic routes for commercial drug production under GMP conditions.

Basic Information

Product Name	5-Ethyl-5-(Isopropylthiomethyl)-1-Methyl-2-Sodiooxy-4,6(1H,5H)-Pyrimidinedione
CAS No.	66968-65-8
Molecular Formula	C11H17N2NaO3S
Molecular Weight	280.32 g/mol
Synonyms	Sodium 5-Ethyl-5-[(isopropylthio)methyl]-1-methylbarbiturate; 1-Methyl-5-ethyl-5-[(isopropylthio)methyl]barbituric Acid Sodium Salt; 5-Ethyl-5-(isopropylthiomethyl)-1-methylbarbituric Acid Sodium Salt; Sodium 5-Ethyl-1-methyl-5-[(propan-2-ylsulfanyl)methyl]-1,3-diazinane-2,4,6-trione; Barbiturate Derivative Sodium Salt; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 5-Ethyl-5-(Isopropylthiomethyl)-1-Methyl-2-Sodiooxy-4,6(1H,5H)-Pyrimidinedione is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.