Description

5-Ethyl-5-Isopentyl-1-Methyl-2-Sodiothio-4,6(1H,5H)-Pyrimidinedione is a specialized thiobarbiturate derivative, a key synthetic intermediate valued for its unique heterocyclic structure. This compound is critical for advanced organic synthesis, particularly in the development of novel pharmaceutical agents and fine chemicals. It is primarily sought by research institutions, pharmaceutical development labs, and fine chemical manufacturers working on central nervous system (CNS) active compounds, anticonvulsants, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of thiobarbiturate and pyrimidinedione-based active pharmaceutical ingredients (APIs).
• CNS Drug Research: Used in the research and development of potential sedative, hypnotic, and anticonvulsant drug candidates.
• Fine Chemical Synthesis: Serves as a versatile precursor for creating complex heterocyclic compounds in advanced organic chemistry.
• Biochemical Research: Employed in studies investigating the structure-activity relationships of barbiturate analogs.
• Reference Standard: Utilized as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	5-Ethyl-5-Isopentyl-1-Methyl-2-Sodiothio-4,6(1H,5H)-Pyrimidinedione
CAS No.	66968-54-5
Molecular Formula	C12H17N2NaO2S
Molecular Weight	276.33 g/mol
Synonyms	5-Ethyl-5-isopentyl-1-methyl-2-thiobarbituric acid sodium salt; Sodium 5-ethyl-5-(3-methylbutyl)-1-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-4,6-dione; 1-Methyl-5-ethyl-5-(3-methylbutyl)-2-thiobarbituric acid sodium derivative; 2-Thio-5-ethyl-5-isopentyl-1-methylbarbituric acid sodium salt; NSC 113986
EINECS	Contact for details

Quality Control

Our production of 5-Ethyl-5-Isopentyl-1-Methyl-2-Sodiothio-4,6(1H,5H)-Pyrimidinedione adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets exacting standards for research and synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.