Description

5-Ethyl-5-(5-Methyl-2-Ethylhexyl)-2-Sodiooxy-4,6(1H,5H)-Pyrimidinedione is a specialized sodium salt derivative of a barbituric acid analog, offering enhanced solubility and stability for advanced chemical synthesis. This compound is valued for its role as a key synthetic intermediate and active pharmaceutical ingredient (API) precursor in the development of central nervous system (CNS) agents. It is primarily required by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions focused on neuropharmacology and medicinal chemistry.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of barbiturate and thiobarbiturate-based active pharmaceutical ingredients (APIs).
• CNS Drug Research: Used in preclinical and research stages for developing sedative, hypnotic, and anticonvulsant drug candidates.
• Fine Chemical Synthesis: Serves as a versatile nucleophile or protected intermediate in multi-step organic synthesis for complex molecules.
• Biochemical Research: Employed in studies investigating GABAA receptor modulation and related neurological pathways.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and impurity profiling.

Basic Information

Product Name	5-Ethyl-5-(5-Methyl-2-Ethylhexyl)-2-Sodiooxy-4,6(1H,5H)-Pyrimidinedione
CAS No.	66968-32-9
Molecular Formula	C15H25N2NaO3
Molecular Weight	304.36 g/mol
Synonyms	5-Ethyl-5-(5-methyl-2-ethylhexyl)barbituric acid sodium salt; Sodium 5-ethyl-5-(5-methyl-2-ethylhexyl)barbiturate; 5-Ethyl-5-(1,3-dimethylbutyl)barbituric acid sodium salt (related isomer); Barbituric acid, 5-ethyl-5-(5-methyl-2-ethylhexyl)-, sodium derivative; 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-(5-methyl-2-ethylhexyl)-, sodium salt; Sodium 5-ethyl-5-(5-methyl-2-ethylhexyl)-2,4,6-trioxohexahydropyrimidine; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our 5-Ethyl-5-(5-Methyl-2-Ethylhexyl)-2-Sodiooxy-4,6(1H,5H)-Pyrimidinedione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure compliance with research and pharmaceutical intermediate standards. Certificates of Analysis (COA) detailing purity, residual solvents, and related substances are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.