Description

β-Endorphin (1-27) is a specific, biologically active fragment of the endogenous opioid peptide β-endorphin. This high-purity peptide is critical for advanced research in neurobiology and pharmacology, serving as a precise tool for studying opioid receptor interactions and pain modulation pathways. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on developing novel therapeutic agents for pain management, addiction, and neurological disorders.

Application

• Neuroscience Research: Used as a reference standard and active agent in studies of opioid receptor binding, signal transduction, and endogenous pain control systems.
• Pharmacological Development: Serves as a key intermediate or reference compound in the discovery and screening of new analgesic drugs and neuropeptide-based therapeutics.
• Biochemical Assays: Employed in enzyme-linked immunosorbent assays (ELISA), radioimmunoassays (RIA), and other in vitro diagnostic tests to quantify endorphin levels.
• Cell Culture Studies: Applied in experimental models to investigate the effects of opioid peptides on cell proliferation, apoptosis, and immune response.
• Academic & Clinical Research: Supports fundamental research into stress response, mood disorders, and the neurochemical basis of addiction.

Basic Information

Product Name	β-Endorphin (1-27)
CAS No.	66954-40-3
Molecular Formula	C₁₄₀H₂₂₀N₄₀O₄₂S
Molecular Weight	3149.6 g/mol
Synonyms	β-Endorphin (1-27); β-Endorphin 1-27; Human β-Endorphin (1-27); Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Ala-Tyr (sequence); β-Lipotropin (61-87); LPH (61-87); ENDB_HUMAN (61-87); Opioid peptide
EINECS	Contact for details

Quality Control

Our β-Endorphin (1-27) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing purity, peptide content, and solvent residues are provided to ensure compliance with research-grade standards and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Analysis	Within ± 10% of theoretical
Solvent Residues	Meets ICH guidelines
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.