Description

5-Allyl-5-[1-(Ethylthio)Ethyl]-2-Sodiooxy-4,6(1H,5H)-Pyrimidinedione is a specialized sodium salt derivative of a barbiturate analog, representing a high-value synthetic intermediate in advanced pharmaceutical manufacturing. This compound matters for its role in the synthesis of complex active pharmaceutical ingredients (APIs), where its unique structure provides critical functionality. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within central nervous system (CNS) and anesthetic drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel barbiturate and thiobarbiturate-derived active pharmaceutical ingredients (APIs).
• CNS Drug Research: Used in preclinical and research stages for developing potential sedative, hypnotic, or anesthetic compounds.
• Chemical Synthesis: Serves as a versatile nucleophile or protected intermediate in multi-step organic synthesis for complex heterocycles.
• Process Chemistry: Employed in scale-up and optimization studies for the production of specialty fine chemicals under GMP-like conditions.

Basic Information

Product Name	5-Allyl-5-[1-(Ethylthio)Ethyl]-2-Sodiooxy-4,6(1H,5H)-Pyrimidinedione
CAS No.	66941-70-6
Molecular Formula	C11H15N2NaO3S
Molecular Weight	278.30 g/mol
Synonyms	5-Allyl-5-(1-ethylthioethyl)barbituric acid sodium salt; Sodium 5-allyl-5-(1-ethylthioethyl)-2,4,6-pyrimidinetrione; 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-allyl-5-(1-(ethylthio)ethyl)-, sodium salt; 5-Allyl-5-(α-(ethylthio)ethyl)barbituric acid sodium derivative; Thiobarbiturate sodium salt intermediate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 5-Allyl-5-[1-(Ethylthio)Ethyl]-2-Sodiooxy-4,6(1H,5H)-Pyrimidinedione is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure compliance with research and development grade standards. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.