Description

5-(2-Cyclopentenyl)-2,3-Dihydro-5-Propyl-2-Thioxo-4,6(1H,5H)-Pyrimidinedione is a specialized heterocyclic organic compound belonging to the thiobarbiturate class, serving as a critical advanced pharmaceutical intermediate and research chemical. Its unique fused-ring structure makes it a valuable building block for synthesizing complex molecules with potential biological activity. This product is essential for pharmaceutical R&D teams, contract research organizations (CROs), and manufacturers of fine chemicals focused on developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel barbiturate and thiobarbiturate analogs for central nervous system (CNS) drug discovery.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to develop new enzyme inhibitors or receptor modulators.
• Fine Chemical Synthesis: Building block for creating complex heterocyclic compounds in custom synthesis and process development.
• Biochemical Research: Potential use in studying GABAergic systems or as a ligand in biochemical assays due to its structural similarity to bioactive molecules.
• Academic Research: Utilized in university and institutional labs for organic synthesis methodology development and chemical education.

Basic Information

Product Name	5-(2-Cyclopentenyl)-2,3-Dihydro-5-Propyl-2-Thioxo-4,6(1H,5H)-Pyrimidinedione
CAS No.	66940-69-0
Molecular Formula	C12H16N2O2S
Molecular Weight	252.33 g/mol
Synonyms	5-(2-Cyclopenten-1-yl)-5-propyl-2-thiobarbituric acid; 5-Propyl-5-(2-cyclopenten-1-yl)-2-thiobarbituric acid; 5-Cyclopenten-5-propylbarbituric-2-thione; 2-Thio-5-(2-cyclopentenyl)-5-propylbarbituric acid; NSC 163044; 5-(2-Cyclopentenyl)-5-propyl-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione
EINECS	Contact for details

Quality Control

Our 5-(2-Cyclopentenyl)-2,3-Dihydro-5-Propyl-2-Thioxo-4,6(1H,5H)-Pyrimidinedione is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.