Description

Poly(Glu,Glu-OMe) 4:1 is a synthetic polypeptide copolymer composed of glutamic acid and its methyl ester derivative in a defined molar ratio. This engineered structure provides a unique platform with tunable charge, solubility, and biodegradability, making it a valuable material for advanced research and development. It is particularly relevant for scientists and formulators in the pharmaceutical, biomedical, and specialty materials sectors seeking functional biopolymers for controlled delivery systems and biomimetic scaffolds.

Application

• Drug Delivery Systems: As a biodegradable and biocompatible carrier for the controlled release of therapeutic agents.
• Biomedical Research: Serving as a model polypeptide or scaffold material for studying cell-material interactions and tissue engineering.
• Polymeric Micelle/Nanoparticle Formation: Utilizing its amphiphilic character to self-assemble into nanostructures for encapsulation.
• Surface Modification: Coating surfaces to improve biocompatibility or introduce specific functional groups.
• Specialty Materials: A precursor for developing novel hydrogels, films, or adhesives with tailored properties.
• Conjugate Chemistry: Acting as a backbone for attaching drugs, targeting ligands, or imaging probes.

Basic Information

Product Name	Poly(Glu,Glu-OMe) 4:1
CAS No.	66844-09-5
Molecular Formula	(C5H7NO3·C6H9NO3)n
Molecular Weight	Variable (Polymer)
Synonyms	Poly(glutamic acid-co-methyl glutamate) 4:1; Poly(L-glutamic acid-co-L-methyl glutamate); PGA-co-PMGA (4:1); Glutamic Acid/Methyl Glutamate Copolymer; Poly(Glu-co-Glu(OMe)); Synthetic Polypeptide Copolymer; Poly(GA-co-MG); Research-Grade Polypeptide
EINECS	Contact for details

Quality Control

Our Poly(Glu,Glu-OMe) 4:1 is produced under controlled conditions to ensure batch-to-batch consistency. Each lot undergoes rigorous analytical testing, including assessment of composition ratio, molecular weight distribution, and purity. A comprehensive Certificate of Analysis (COA) detailing specific results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric humidity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Composition Ratio (Glu:Glu-OMe)	~4:1 (Molar)
Identification (IR)	Conforms
Assay (Amino Acid Analysis)	≥ 95%
Moisture Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.