Description

3-Nitro-L-Tyrosine Ethyl Ester Hydrochloride is a chemically modified derivative of the amino acid tyrosine, specifically designed for research and synthesis applications. This compound is valued for its role as a key intermediate and biochemical probe in advanced pharmaceutical and life science research. It is primarily utilized by researchers and process chemists in the pharmaceutical, biotechnology, and academic sectors for developing novel therapeutic agents and studying enzyme mechanisms.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of more complex drug candidates and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving tyrosine kinases or nitric oxide synthase pathways.
• Peptide Synthesis: Serves as a protected and activated tyrosine derivative in solid-phase and solution-phase peptide chemistry.
• Proteomics & Labeling Studies: Acts as a chemical tag or modification site for studying protein structure, function, and post-translational modifications.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	3-Nitro-L-Tyrosine Ethyl Ester Hydrochloride
CAS No.	66737-54-0
Molecular Formula	C11H15N2O5 • HCl
Molecular Weight	300.71 g/mol (Free base: 265.25 g/mol)
Synonyms	L-Tyrosine, 3-nitro-, ethyl ester, hydrochloride; Ethyl 3-nitro-L-tyrosinate hydrochloride; 3-Nitro-L-tyrosine ethyl ester HCl; 3-Nitrotyrosine ethyl ester hydrochloride; (2S)-2-Amino-3-(4-hydroxy-3-nitrophenyl)propanoic acid ethyl ester hydrochloride; NO2-Tyr-OEt • HCl; NTEE • HCl
EINECS	Contact for details

Quality Control

Our 3-Nitro-L-Tyrosine Ethyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation. A Certificate of Analysis (COA) detailing all specifications and test results is provided to ensure traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.