Description

H-Tyr-Gly-Gly-Oh H2O is a tripeptide derivative, specifically a tyrosine-glycine-glycine sequence with a free C-terminal carboxylic acid and a hydrated form. This compound serves as a crucial building block and intermediate in advanced organic synthesis and peptide research. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions for developing novel therapeutic agents and conducting biochemical studies.

Application

• Pharmaceutical Intermediate: Key starting material or building block for the synthesis of more complex peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a substrate, standard, or model compound in enzymatic studies, receptor-ligand binding assays, and metabolic pathway investigations.
• Peptide Synthesis: Essential raw material in solid-phase and solution-phase peptide synthesis for constructing longer peptide chains with specific sequences.
• Neuroscience Studies: Potential utility in research related to neuropeptides and neuromodulators due to the presence of the tyrosine residue.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	H-Tyr-Gly-Gly-Oh H2O
CAS No.	66723-82-8
Molecular Formula	C₁₄H₁₉N₃O₆ • xH₂O
Molecular Weight	325.32 g/mol (anhydrous basis)
Synonyms	L-Tyrosylglycylglycine; Tyr-Gly-Gly; YGG; H-Tyr-Gly-Gly-OH hydrate; N-(2-{2-[(2S)-2-Amino-3-(4-hydroxyphenyl)propanamido]acetamido}acetic acid hydrate; Tyrosine-Glycine-Glycine tripeptide; Glycylglycyl-L-tyrosine; L-Tyrosine-Gly-Gly
EINECS	Contact for details

Quality Control

Our H-Tyr-Gly-Gly-Oh H2O is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) documenting purity, water content, and other critical parameters are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.