Description

Pyridine-2-Sulfonyl Chloride is a versatile and highly reactive sulfonylating agent, a key building block in advanced organic synthesis. Its core value lies in its ability to efficiently introduce the pyridine-2-sulfonyl moiety, a crucial functional group for modulating the properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical reagent for the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Peptide Modification: Employed as a sulfonylating agent for amino acid side chains in peptide chemistry and bioconjugation.
• Material Science Precursor: Serves as a building block for creating functional polymers, ligands for catalysis, and advanced organic frameworks.
• Chemical Research & Development: A fundamental tool in medicinal chemistry and process chemistry for structure-activity relationship (SAR) studies.
• Dye and Pigment Manufacturing: Used in the synthesis of specialized sulfonated colorants and photoactive compounds.

Basic Information

Product Name	Pyridine-2-Sulfonyl Chloride
CAS No.	66715-65-9
Molecular Formula	C5H4ClNO2S
Molecular Weight	177.61 g/mol
Synonyms	2-Pyridinesulfonyl chloride; Picolinesulfonyl chloride; 2-Pyridylsulfonyl chloride; Pyridine-2-sulfonic acid chloride; Picolinic acid sulfonyl chloride; 2-Chlorosulfonylpyridine; Pyridine-2-SO2Cl
EINECS	Contact for details

Quality Control

Our Pyridine-2-Sulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.