Description

o-Acetyl-L-Serine Hydrochloride is a protected derivative of the amino acid L-serine, specifically designed for advanced peptide synthesis and biochemical research. This compound is valued for its role as a key chiral building block, enabling the controlled introduction of serine residues while protecting reactive side-chain functionalities. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutic peptides and conducting metabolic studies.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the solid-phase and solution-phase synthesis of complex peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a substrate or precursor in enzymatic studies, metabolic pathway analysis, and proteomics research.
• Peptide Synthesis: Serves as a protected serine derivative to prevent unwanted side reactions during the sequential assembly of custom peptides.
• Fine Chemical Production: Employed in the manufacture of specialized agrochemicals, diagnostics, and other high-value organic compounds requiring specific chirality.

Basic Information

Product Name	o-Acetyl-L-Serine Hydrochloride
CAS No.	66638-22-0
Molecular Formula	C5H10ClNO4
Molecular Weight	183.59 g/mol
Synonyms	O-Acetyl-L-serine hydrochloride; L-Serine, O-acetyl-, hydrochloride; Acetylserine hydrochloride; (S)-2-Acetamido-3-hydroxypropanoic acid hydrochloride; N-Acetyl-L-serine hydrochloride; Serine O-acetate hydrochloride; 2-Acetamido-3-hydroxypropionic acid hydrochloride; O-Acetylserine HCl
EINECS	Contact for details

Quality Control

Our o-Acetyl-L-Serine Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for research and synthesis applications. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]20/D: Specific range provided on COA
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.