Description

2-(5-Bromopyrimidin-2-Yl)Malonic Acid Diethyl Ester is a high-purity brominated pyrimidine derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a reactive bromine atom and a malonate ester moiety, makes it an exceptionally versatile intermediate for constructing complex heterocyclic systems. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Building block for creating functionalized polymers and advanced organic electronic materials.
• Chemical Biology: Employed in the synthesis of molecular probes and labeled compounds for biochemical research.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs for bespoke chemical manufacturing.

Basic Information

Product Name	2-(5-Bromopyrimidin-2-Yl)Malonic Acid Diethyl Ester
CAS No.	66621-92-9
Molecular Formula	C11H13BrN2O4
Molecular Weight	317.14 g/mol
Synonyms	Diethyl 2-(5-bromopyrimidin-2-yl)malonate; 2-(5-Bromo-2-pyrimidinyl)malonic Acid Diethyl Ester; Diethyl (5-Bromopyrimidin-2-yl)malonate; Malonic acid, 2-(5-bromo-2-pyrimidinyl)-, diethyl ester; 66621-92-9; 5-Bromo-2-pyrimidinylmalonic acid diethyl ester
EINECS	Contact for details

Quality Control

Our 2-(5-Bromopyrimidin-2-Yl)Malonic Acid Diethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.