Description

2-(4-Bromopyrimidin-2-yl)acetic acid is a high-purity brominated pyrimidine derivative, serving as a versatile and critical building block in advanced organic synthesis. Its value lies in the reactive bromine atom and acetic acid moiety, which enable precise functionalization for creating complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Ligand & Catalyst Synthesis: Employed to create specialized ligands for metal catalysis and organocatalysts.
• Material Science: Serves as a monomer or functionalizing agent for advanced polymers and organic electronic materials.
• Chemical Biology: Utilized in the design and synthesis of molecular probes and bio-conjugates for biochemical studies.
• Custom Synthesis: A fundamental starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis projects.

Basic Information

Product Name	2-(4-Bromopyrimidin-2-yl)acetic Acid
CAS No.	66621-83-8
Molecular Formula	C6H5BrN2O2
Molecular Weight	217.02 g/mol
Synonyms	2-(4-Bromopyrimidin-2-yl)acetic acid; Acetic acid, 2-(4-bromo-2-pyrimidinyl)-; 4-Bromo-2-pyrimidineacetic acid; (4-Bromopyrimidin-2-yl)acetic acid; 66621-83-8; 2-(4-Brom-2-pyrimidinyl)essigsäure (German); Acide 2-(4-bromo-2-pyrimidinyl)acétique (French)
EINECS	Contact for details

Quality Control

Every batch of 2-(4-Bromopyrimidin-2-yl)acetic acid is manufactured under a strict quality management system and undergoes rigorous analytical testing to ensure consistency and high purity. Our standard quality commitment includes comprehensive characterization by HPLC, NMR, and MS to confirm identity and purity. Certificates of Analysis (COA) detailing all test results are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The product is light-sensitive and should be handled and stored away from strong light sources. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.