Description

Somatostatin, Cys(3)- is a synthetic cyclic peptide analog of the endogenous hormone somatostatin, featuring a cysteine residue at position 3. This modification is critical for enhancing receptor binding affinity and metabolic stability, making it a valuable research and development tool. It is primarily utilized by pharmaceutical researchers, biotech companies, and academic institutions engaged in endocrinology, oncology, and metabolic disease studies.

Application

• Pharmaceutical Research & Development: As a reference standard and active pharmaceutical ingredient (API) in the development of novel somatostatin receptor-targeted therapies.
• Biochemical Assays: For studying somatostatin receptor (SSTR) subtypes, their signaling pathways, and ligand-receptor interactions in vitro.
• Endocrinology Studies: Investigation of hormonal regulation, particularly the inhibition of growth hormone, insulin, and glucagon secretion.
• Oncology Research: Exploration of therapeutic applications in neuroendocrine tumors (NETs) and other cancers expressing somatostatin receptors.
• Peptide Chemistry & Conjugation: Serves as a key intermediate or scaffold for further chemical modification, such as radiolabeling or conjugation with other molecules for diagnostic or therapeutic purposes.
• Academic & Clinical Research: Used in laboratory experiments to understand the physiological and pathological roles of somatostatin.

Basic Information

Product Name	Somatostatin, Cys(3)-
CAS No.	66610-27-3
Molecular Formula	C76H104N18O19S2
Molecular Weight	1637.9 g/mol
Synonyms	Cys(3)-Somatostatin; Somatostatin-14 (Cys3); H-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH (cyclic 3-14 disulfide); Cyclo(3-14)[Cys3,Cys14]somatostatin; SRIF-14 (Cys3); Somatotropin release-inhibiting factor analog; L-Cysteinylsomatostatin; [Cys3]-Somatostatin
EINECS	Contact for details

Quality Control

Our Somatostatin, Cys(3)- is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide Certificates of Analysis (COA) with each shipment, detailing all test results to ensure compliance with your research specifications. Our quality commitment supports applications requiring high-purity peptide references and intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to reach room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 8.0%
Peptide Content	≥ 70.0%
Amino Acid Analysis	± 10% of theoretical

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.