Description

Somatostatin, 5-Fluoro-Trp(8)- is a synthetic, fluorinated analog of the endogenous peptide hormone somatostatin. This modification enhances its metabolic stability and receptor binding affinity, making it a valuable tool for advanced biochemical and pharmacological research. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and diagnostic developers in the fields of endocrinology, oncology, and neuroscience.

Application

• Biochemical Research: Used as a potent and selective ligand for studying somatostatin receptor (SSTR) subtypes, their signaling pathways, and downstream effects.
• Drug Discovery & Development: Serves as a reference compound or a lead structure in the development of novel therapeutics targeting neuroendocrine tumors, acromegaly, and diabetic retinopathy.
• In Vitro Diagnostics (IVD): Employed in the development and calibration of immunoassays and receptor-binding assays for hormone level quantification.
• Metabolic Studies: Investigates the inhibitory effects on the secretion of growth hormone, insulin, and glucagon in experimental models.
• Neuroscience Research: Applied in studies exploring the role of somatostatin in neurotransmission, neural development, and related neurological disorders.
• Academic & Institutional Research: A key reagent for university and government laboratory projects focused on peptide chemistry, hormone biology, and molecular pharmacology.

Basic Information

Product Name	Somatostatin, 5-Fluoro-Trp(8)-
CAS No.	66582-76-1
Molecular Formula	C76H104FN18O19S2
Molecular Weight	1633.9 g/mol
Synonyms	5-Fluoro-D-Tryptophan(8)-Somatostatin; [5-F-D-Trp8]-Somatostatin; Somatostatin (5-fluoro-D-tryptophan8); H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-5-F-D-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH (cyclic 3-14 disulfide); SRIF analog (5-F-D-Trp8); SST-14 analog
EINECS	Contact for details

Quality Control

Our Somatostatin, 5-Fluoro-Trp(8)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). Certificates of Analysis (COA) detailing all specifications and test results are available upon request to ensure full traceability and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Peptide Content	≥ 80.0%
Water Content (KF)	≤ 8.0%
Acetate Content (HPLC)	≤ 15.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.