Description

L-Tyr-D-Ser-Gly-L-Phe-L-Leu-Ome is a synthetic pentapeptide derivative with a specific sequence and C-terminal methyl ester modification. This compound is a valuable research-grade biochemical building block, offering a precisely defined structure for scientific investigation. It is primarily utilized by researchers and developers in the pharmaceutical and biotechnology sectors for applications in peptide chemistry, structure-activity relationship (SAR) studies, and as a potential intermediate in the synthesis of more complex bioactive molecules.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or reference standard in the synthesis and study of novel peptide-based therapeutics.
• Biochemical Research: Used as a substrate or model compound in enzymatic studies, receptor binding assays, and metabolic pathway investigations.
• Structure-Activity Relationship (SAR) Studies: The defined sequence and D-Ser configuration make it a crucial tool for understanding how specific amino acid alterations affect biological activity and stability.
• Peptide Library Construction: Acts as a building block in the combinatorial synthesis of peptide libraries for high-throughput screening against biological targets.
• Academic Research: Employed in university and institutional labs for fundamental studies in organic chemistry, peptide synthesis methodologies, and molecular biology.

Basic Information

Product Name	L-Tyr-D-Ser-Gly-L-Phe-L-Leu-Ome
CAS No.	66547-12-4
Molecular Formula	C34H46N6O9
Molecular Weight	682.77 g/mol
Synonyms	Tyr-D-Ser-Gly-Phe-Leu-OMe; L-Tyrosyl-D-seryl-glycyl-L-phenylalanyl-L-leucine methyl ester; H-Tyr-D-Ser-Gly-Phe-Leu-OMe; Pentapeptide TFA salt (if applicable); Y-D-S-G-F-L-OMe; 66547-12-4; Methyl L-tyrosyl-D-serylglycyl-L-phenylalanyl-L-leucinate
EINECS	Contact for details

Quality Control

Our L-Tyr-D-Ser-Gly-L-Phe-L-Leu-Ome is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity determination, MS for identity confirmation, and chiral analysis to verify the D-Ser configuration. We provide full traceability and a detailed Certificate of Analysis (COA) with every shipment, ensuring compliance with research-grade specifications and supporting your critical R&D work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Chiral Purity (D-Ser)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.