Description

2,6-Dimethyl-5,6,7,8-tetrahydro-pyrido[4,3-d]pyrimidine is a high-purity heterocyclic organic compound with the CAS number 66521-81-1, serving as a critical advanced pharmaceutical intermediate. Its value lies in its complex bicyclic pyridopyrimidine structure, which is a privileged scaffold in medicinal chemistry for developing bioactive molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for synthesizing novel drug candidates targeting various therapeutic areas.

Application

This versatile intermediate is primarily utilized in sophisticated organic synthesis. Key application areas include:

• Pharmaceutical Intermediate: A key building block for the synthesis of potential active pharmaceutical ingredients (APIs), especially in kinase inhibitor research.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to discover new therapeutic agents.
• Agrochemical Development: Serves as a precursor in the creation of novel pesticides and herbicides, leveraging its heterocyclic core.
• Chemical Biology Probes: Employed in the development of molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	2,6-Dimethyl-5,6,7,8-tetrahydro-pyrido[4,3-d]pyrimidine
CAS No.	66521-81-1
Molecular Formula	C9H13N3
Molecular Weight	163.22 g/mol
Synonyms	2,6-Dimethyl-5,6,7,8-tetrahydro-1H-pyrido[4,3-d]pyrimidine; 5,6,7,8-Tetrahydro-2,6-dimethylpyrido[4,3-d]pyrimidine; Pyrido[4,3-d]pyrimidine, 5,6,7,8-tetrahydro-2,6-dimethyl-; 2,6-Dimethyl-5,6,7,8-tetrahydro-pyrido[4,3-d]pyrimidine; SCHEMBL11821027; DTXSID60674469; AKOS025310647; A893841
EINECS	Contact for details

Quality Control

Our 2,6-Dimethyl-5,6,7,8-tetrahydro-pyrido[4,3-d]pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment ensures the material meets the stringent requirements for pharmaceutical R&D and other critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.