Description

6-tert-Butyl-5,6,7,8-Tetrahydroquinazolin-2-Amine is a high-purity, functionalized tetrahydroquinazoline derivative, a versatile building block in advanced organic synthesis. Its value lies in its unique sterically hindered amine and heterocyclic structure, which is critical for modulating the biological activity and physicochemical properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine-tuning molecular interactions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Serves as a core scaffold for developing new herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Ligand & Catalyst Development: Used in the creation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the synthesis of advanced organic electronic materials and functional polymers.
• Chemical Biology Probe: Utilized as a molecular tool to study enzyme function and protein-protein interactions in biochemical pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring complex, multi-step heterocyclic chemistry.

Basic Information

Product Name	6-tert-Butyl-5,6,7,8-Tetrahydroquinazolin-2-Amine
CAS No.	66521-78-6
Molecular Formula	C₁₂H₁₉N₃
Molecular Weight	205.30 g/mol
Synonyms	2-Amino-6-tert-butyl-5,6,7,8-tetrahydroquinazoline; 6-(tert-Butyl)-5,6,7,8-tetrahydroquinazolin-2-amine; 5,6,7,8-Tetrahydro-6-(1,1-dimethylethyl)-2-quinazolinamine; 6-tert-Butyl-5,6,7,8-tetrahydro-2-quinazolinamine; 2-Quinazolinamine, 5,6,7,8-tetrahydro-6-(1,1-dimethylethyl)-; 6-tert-Butyl-5,6,7,8-tetrahydroquinazolin-2-ylamine
EINECS	Contact for details

Quality Control

Every batch of 6-tert-Butyl-5,6,7,8-Tetrahydroquinazolin-2-Amine undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality management system is designed to meet the stringent requirements of research and cGMP manufacturing environments. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥97% by HPLC), identity confirmation (by IR, NMR), and impurity profiles is provided with each shipment to support your regulatory and R&D documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.