Description

Pyrimidine, 2-((5-Nitro-2-Pyridinyl)Thio)- is a specialized heterocyclic organic compound featuring a pyrimidine core linked to a nitropyridine moiety via a thioether bridge. This unique molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting specific enzymatic pathways.
• Medicinal Chemistry Research: Serves as a core scaffold or a functionalized fragment for constructing compound libraries in drug discovery programs.
• Agrochemical Development: Used in research for creating new active ingredients for crop protection products.
• Chemical Biology Probes: Utilized in the development of molecular probes to study biological processes and protein interactions.
• Material Science Research: Investigated as a potential monomer or additive for creating specialized polymers with unique electronic or thermal properties.

Basic Information

Product Name	Pyrimidine, 2-((5-Nitro-2-Pyridinyl)Thio)-
CAS No.	66474-51-9
Molecular Formula	C9H6N4O2S
Molecular Weight	234.23 g/mol
Synonyms	2-((5-Nitro-2-pyridinyl)thio)pyrimidine; 2-[(5-Nitropyridin-2-yl)sulfanyl]pyrimidine; 2-(5-Nitro-2-pyridylthio)pyrimidine; 5-Nitro-2-(pyrimidin-2-ylsulfanyl)pyridine; 2-(5-Nitropyridin-2-ylthio)pyrimidine; 2-Pyrimidinyl 5-nitro-2-pyridyl sulfide; 66474-51-9
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized and tested to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing results from analytical methods such as HPLC, NMR, and mass spectrometry. We support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.