Description

2(1H)-Pyrimidinethione, 4-(4-Methoxyphenyl)-6-Phenyl- is a specialized heterocyclic organic compound belonging to the pyrimidinethione class, serving as a key synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in advanced pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for synthesizing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of potential drug candidates, especially those targeting kinase inhibition or other biological pathways.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, or plant growth regulators that require a pyrimidine-thione core structure.
• Material Science Precursor: Serves as a starting material for creating organic electronic materials, ligands for metal-organic frameworks (MOFs), or specialty polymers.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying enzyme function or protein interactions.
• Academic & Institutional Research: Utilized in universities and research institutes for methodological studies in heterocyclic chemistry and new reaction development.
• Custom Synthesis & Contract Manufacturing: A key substrate for fine chemical manufacturers offering bespoke synthesis services to clients in life sciences.

Basic Information

Product Name	2(1H)-Pyrimidinethione, 4-(4-Methoxyphenyl)-6-Phenyl-
CAS No.	66443-37-6
Molecular Formula	C17H14N2OS
Molecular Weight	294.37 g/mol
Synonyms	4-(4-Methoxyphenyl)-6-phenyl-2(1H)-pyrimidinethione; 4-(4-Methoxyphenyl)-6-phenyl-1H-pyrimidine-2-thione; 6-Phenyl-4-(p-methoxyphenyl)-2-mercaptopyrimidine; 4-(p-Methoxyphenyl)-6-phenyl-2-pyrimidinethiol; 4-(4-Methoxyphenyl)-6-phenylpyrimidine-2-thiol; 2-Mercapto-4-(4-methoxyphenyl)-6-phenylpyrimidine; 2-Thioxo-4-(4-methoxyphenyl)-6-phenyl-1,2-dihydropyrimidine
EINECS	Contact for details

Quality Control

Our 2(1H)-Pyrimidinethione, 4-(4-Methoxyphenyl)-6-Phenyl- is produced under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and physical characteristics are provided and available upon request. We adhere to cGMP principles where applicable to support our clients' regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single unknown impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.